Toronto leads with the highest homicide rate of the ten major cities.
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| City | Population | Homicides | 2018 | Proj. Homicides | 2017 |
| Projection | per 100K | Homicides | Toronto | 2731571 | 59 | 101.6 | 3.7 | 63 | Montreal | 1704694 | 16 | 27.5 | 1.6 | 24 | Calgary | 1239220 | 7 | 12.1 | 1.0 | 28 | Ottawa | 934243 | 13 | 22.4 | 2.4 | 14 | Edmonton | 932546 | 18 | 31.0 | 3.3 | 42 | Mississauga | 721599 | 4 | 6.9 | 1.0 | 9 | Winnipeg | 705224 | 11 | 18.9 | 2.7 | 21 | Vancouver | 631486 | 12 | 20.7 | 3.3 | 17 | Brampton | 593638 | 11 | 18.9 | 3.2 | 6 | Hamilton | 536917 | 3 | 5.2 | 1.0 | 10 |